ArcGIS Desktop supports high-contrast mode, which is a Windows operating system setting.
The readability of the ArcGIS Desktop user interface can be improved by turning on high-contrast mode. The system color scheme increases the color contrast of text, menus, tabs, and icons to make them more distinct and easier to identify for users with low vision or color blindness. However, high-contrast mode does not change the appearance of certain views in ArcGIS Desktop, such as maps and layouts.
You should close any open ArcGIS Desktop sessions before you turn on high-contrast mode. Restart ArcGIS Desktop after high-contrast mode has been turned on.
To turn on high-contrast mode, press left Shift+left Alt+PrtScn on your keyboard and click Yes on the High Contrast prompt.
To turn off high-contrast mode, use the same keyboard shortcut: left Shift+left Alt+PrtScn.
For other ways to turn on high-contrast mode, see Use high contrast mode on the Microsoft Support site.